Vial for medicinal and laboratory preparations.



H. FEIGNOUX,

Patente Oct. 24, 1916.

VIAL FOR MEDICINAL AND LABORATORY PREPARATIONS.

APPLICATION r|LED1uNE15,19|4. RENEWED sEPT.19. |916.

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RAOUL FEIGNOUX, or MoNTnEUrL-soos-iaors, FRANCE.

VIAL FOR MEDICINAL AND LABORATORY PREARATIONS.

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Application filed. June 15, 1914, Serial No. 845,252.

To all whom t may concern.'

Be it known that T, RAOUL FnrGNoUX, a citizen of the Republic of France,residing in Montreuil-sous-Bois, France, have invented certain new anduseful Improvements in Vials for Medicinal and Laboratory Preparations,of which the following is a specification.

Numerous pharmaceutical preparations and remedial substances, andparticularly serums for hypodermic treatment are placed on the market ina. perfectly sterile condition, in glass vials having usually two endseach drawn to a point and sealed. At'the moment of using the-preparationor remedial substance, one of the sealed points is'broken by the userfor the purpose of inserting therein the needle of a syringe and thendrawing in by suction the contents of the vial into the syringe. Inspite of all precautions and expedients for insuring asepsis which aregenerally adopted in disinfecting or sterilizing the syringe and passingthe needle through a iame, cases of infection of the treated tissues ofthe patient have frequently occurred due to the introduction ofpathogenic germs during the injecting operation.

It was soon discovered that the infecting of the preparation or remedialsubstance was caused by the bubbles of air passing into the vial for thepurpose of replacing the liquid preparation drawn into the syringe incharging the latter. This charging is done usually in the sick chamberor in the hospital ward or operating theater, where the atmosphere isloaded with microbes and pathogenie germs and, therefore, it is obviousthat the air bubbles entering through the broken point of the vial incounterflow of the liquid preparation which is being drawn into thesyringe, and which pass completely through the said liquid, mustnecessarily carry pathogenic germs into the midst of the said liquidpreparation, thereby utterly destroying all the aseptic precautions, andthe more so, the larger the capacity of the vial. With the object ofremedying these drawbacks, which are extremely serious from both medicaland surgical points of view, various types of self-injecting vials havebeen proposed which enable the preparation, remedial substance or serumto pass directly through the end of the vial into the tissues of thepatient, with the object of avoiding the risk of in- Speccaticn ofLetters Patent.

Patented Uct. 2d, T916.

Renewed september 19, 191e.v serial No. 121,095.

fecting the `liquid preparation by having i i to pass first through asyringe.

Vials of that type are, however, attended by numerous difliculties inuse, namely: They are more delicate and complicated to handle, and theyrequire rather more skill and experience, and further they are verydear, while they do not allow the use of ordinary syringes.

Now the present invention has for its object toprovide an improved vialfor serums and the like, which shall solve completely the problem ofinsuring an absolutelyv perfect asepsis, by obviating all bubbling `upof the air through the serum, and `which shall also be capable of beingused with any type of syringe. The improved vial is eX- tremely simplein construction without however requiring any change in the usual methodof operating.

This invention is illustrated by way of example in the accompanyingdrawing, in which:

Figure l is a side elevation of an improved vial of the cylindrical tubetype, and Fig. 2 is a side elevation, illustrating the same vial in usewith a syringe during the operation of transferring the serum or thelike from the vial into the syringe.

The improved vial consists of a suitable glass container a which may beof cylindrical form as shown, or of any other suitable form, forinstance, pearshaped, ovoid, etc., according to the quantity of serum tobe contained. It has at its upper end an ordinary point which has beendrawn fine and sealed by means of a blowpipe flame, and at its lower enda slender tubular extension c, which has been folded back verticallyalong the side of the container a. This tubular extension is likewisedrawn to a fine point and preferably sealed by means of a blowpipevflame. The processes for charging the improved vial and sterilizing itscontents in 'the digester are the same as for ordinary vials.

To use the improved vial, the points of its ends 'Z9 and c are broken,and the needle of the syringe Z is inserted into the hole in theextension c, which is thus completely closed up by the needle. Thesuction of the syringe will then cause the serum to rise in the syringe,while the level of the serum in the container a will fall accordingly.Air will enter through the broken point b in the direction ofthe arrowand Will ll the space left by the serum at the same rate as the v latteris sucked'away by the syringe, but

without any risk of the air bubbling through the serum, so that there isno possibility of the serum becoming infected thereby.`

As usual, the whole of the serum is not drawn to the last drop into thesyringe, so that the portion of serum which has come in direct contactwith the air will remain in the vial, and is further separated from theoutside air by a certain quantity of sterilized airrernainingf in thevial. By this means the serum or the like has been transferred into thesyringe under exactly the same conditions of asepsis as it Was whilecontained in the vial. Y Having now particularly described andascertained the nature of my said invention, I declare that what I claimis:

1. A vial for serum and the like, comprising in combination with thewide container 'for the serum, a pointed upper end and a pointed lowerend of restricted cross section bent back upon said container andadapted t0 have its point broken ofil for the reception of aserum, saidpoint at the upper end being` also adaptedto be broken oli for admittingair at that level of the serum not being fed into the syringe,substantially as described.

2. A vial for serum and the like for preventing infection of the serumduring the transmission of the latter into ak needle syringe comprising`a Wide container having two sealed pointed ends, one of which has theform of a iine bore a tubular extension of restricted cross section bentback upon the side of the container, into which extension when the pointis broken, the needle of a syringe can be inserted for drawing` up theserum or the like, the other end adapted to be broken ofl1 for admittingair to that level of the serum not to be fed into the syringe.

In testimony whereof I aflix my signature in presence of two witnesses.

RAOUL FEIGNOUX.

yWitnesses: CHAs. P. PREssLY, .EDWARD WOLF.

Copies oi' this patent may be obtained for ive cents each, by addressingthe "Commissioner of Patents, Washington, D. C.

